Our Research Projects

Rxcelerate Research

This is a project which is currently making use of HPC facilities at Newcastle University. It is active.

Project Contacts

For further information about this project, please contact:


Project Description

This project focuses on structure-based drug discovery for RxCelerate, including large-scale virtual screening, molecular docking, molecular dynamics simulations, and binding mode refinement to identify and prioritize small-molecule hits for experimental validation across multiple protein targets.


Software or Compute Methods

DOCK6 and Smina are used for docking and virtual screening, Python and PyTorch for custom analysis pipelines, and GROMACS 2024 for MD simulations, with in-house workflows executed at scale on HPC clusters using SLURM.