Our Research Projects

Computer-aided drug design

This is a project which is currently making use of HPC facilities at Newcastle University. It is active.

Project Contacts

For further information about this project, please contact:


Project Description

Simulations for computer-aided drug design. Simulation types include high-throughput de novo design and free energy calculations, as well as related quantum mechanical and machine learning potential simulations for force field assignment.


Software or Compute Methods

- psi4 quantum chemistry

- OpenMM and Gromacs molecular dynamics

- OpenFE and BioSimSpace for free energy calculations

- OpenFF toolkit for force field parameterisation