This is a project which is currently making use of HPC facilities at Newcastle University. It is active.
For further information about this project, please contact:
This project will utilise long-read sequencing data (ONT and PacBio) and custom bioinformatic pipelines to assemble and characterise dicentric chromosomes from cancer samples.
DNA sequence basecalling using GPU-accelerated nodes and ONT-provided software (Dorado). Custom pipelines will be developed using open-source packages for genome assembly such as hifiasm, verkko and flye. Long-read whole-genome sequencing data will be routinely analysed for structural variation, SNPs and methylation analysis using the most-to-date packages available.