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  3. The human RNA exosome

The human RNA exosome

This is a project which is currently making use of HPC facilities at Newcastle University. It is active.

Project Contacts

For further information about this project, please contact:


Project Description

Computational Analysis of RNAseq and Nanopore sequencing data from human cell lines with mutant or depleted RNA exosome (EXOSC) subunits.


Software or Compute Methods

FastQC (https://github.com/s-andrews/FastQC);

STAR (https://github.com/alexdobin/STAR);

Java (https://www.java.com/en/download/help/linux_x64_install.html);

picard (https://github.com/broadinstitute/picard/releases/tag/3.1.1);

SAMtools (http://github.com/samtools/samtools);

BEDTools (https://github.com/arq5x/bedtools2);

HTSeq (https://htseq.readthedocs.io/en/master/install.html);

R (https://cran.r-project.org/bin/linux/ubuntu/fullREADME.html);
GATK (https://gatk.broadinstitute.org/hc/en-us/articles/360036194592-Getting-started-with-GATK4);

Perl (https://www.perl.org/get.html);

Python (https://www.python.org/downloads/